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1 OMIM reference -
1 associated gene
7 signs/symptoms
PROTEIN INTERACTIONS: 1
1 OMIM reference -
1 associated gene
No signs/symptoms info
Denys-Drash syndrome
Adrenocortical carcinoma

WT1 TP53


INTERACTOME
ASSOCIATIONS

(click on a score value to see the evidence)
WT1
(0.86)
TP53



Citations in the biomedical literature:


Denys-Drash syndrome
WT1
Adrenocortical carcinoma
TP53



Denys-Drash syndrome
Adrenocortical carcinoma

Synonym(s):
- Drash syndrome
- Wilms tumor and pseudohermaphroditism

Synonym(s):
(no synonyms)

Classification (Orphanet):
- Rare developmental defect during embryogenesis
- Rare endocrine disease
- Rare genetic disease
- Rare gynecologic or obstetric disease
- Rare oncologic disease
- Rare renal disease
- Rare urogenital disease
Classification (Orphanet):
- Rare circulatory system disease
- Rare endocrine disease
- Rare infertility
- Rare oncologic disease
- Rare renal disease

Classification (ICD10):
- Diseases of the genitourinary system -
Classification (ICD10):
- Endocrine, nutritional and metabolic diseases -

Epidemiological data:
(no data available)
Epidemiological data:
Class of prevalence: 1-9 / 1 000 000
Average age onset: childhood
Average age of death: -
Type of inheritance: sporadic

External references:
1 OMIM reference -
1 MeSH reference: D030321
External references:
1 OMIM reference -
1 MeSH reference: D018268

Denys-Drash syndrome

Very frequent
- Male pseudohermaphrodism / lack of virilisation
- Nephroblastoma / Wilms tumor
- Nephrotic syndrome
- Proteinuria
- Renal disease / nephropathy

Frequent
- Chronic arterial hypertension

Occasional
- Mixed gonadal dysgenesis


Adrenocortical carcinoma

(no data available)